Trends in Medicine: November News Roundup 2017

November 30, 2017

Stay current on the latest medical news and trends!

Here are some of the stories that made headlines in November from Harvard Medical School and our affiliated hospitals, instructors, and researchers:

Consumer Health Threatened by Bodybuilding Products – Reuters
Shalender Bhasin (HMS/Brigham and Women’s) co-authored a study indicating that one in four products marketed as nonsteroidal selective androgen receptor modulators (SARMs) “contained ingredients that weren’t on the label, including potentially dangerous drugs, and 59 percent had more or less than the advertised amounts of certain ingredients.”
Read: Bodybuilding products sold online may be mislabeled or unsafe by Lisa Rappaport

Global Health Funding and Cryptocurrencies – HMS Paper Chase
John Meara (HMS/Boston Children’s) has co-authored this paper which outlines and provides “examples for at least four important ways in which this potential disruption of traditional global health funding mechanisms could occur…”
Read: From blockchain technology to global health equity: can cryptocurrencies finance universal health coverage?

Type 1 Diabetes Halted in Mouse Models – The Scientist
Paolo Fiorina (HMS/Boston Children’s), is the lead author of this research showing, “the immune systems of both diabetic mice and humans lack a suppressor protein called programmed death ligand 1 (PD-L1), which normally keeps T cell activity in check. Raising levels of PD-L1 in immune stem cells restored these cells’ ability to tame T cells in culture and to prevent hyperglycemia when transferred into diabetic mice.”
Read: Immune Checkpoint Found Lacking in Type 1 Diabetes by Ruth Williams

Reducing Stigma Necessary to Treat Opioid Use Disorder – The New Yorker
Jerome Groopman (HMS/Beth Israel Deaconess) authored this honest and insightful article discussing how health care providers are, “moving past implicit biases, stigma, and fear to connect with our patients and respond to a defining crisis of our time.”
Read: What’s Missing from the National Discussion About the Opioid Epidemic

Modeling Cancer Mutations – HMS Paper Chase
Shamil Sunyaev (HMS/Brigham and Women’s) and Donate Weghorn (HMS/Brigham and Women’s) authored this paper in which they “present a hierarchical framework that allows modeling of coding point mutations. Application of the model to sequencing data from 17 cancer types demonstrates an increased power to detect known cancer driver genes and identifies new significantly mutated genes with highly plausible biological functions.”
Read: Bayesian inference of negative and positive selection in human cancers

New CME courses available on HMS Global Academy in December:


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