Procalcitonin-Guided Antibiotic Therapy in Lower Respiratory Tract Infection: Is It Safe?

By Martina McGrath, MD
June 5, 2018

Pulmonary infection is one of the most common reasons for hospitalization in the US. Overprescription of antibiotics, due either to inappropriate initiation or excessive treatment duration, is an important contributor to antibiotic resistance and complications of therapy.1.2 Continue reading “Procalcitonin-Guided Antibiotic Therapy in Lower Respiratory Tract Infection: Is It Safe?”

Does High-Sensitivity Cardiac Troponin Predict Future Cardiac Events?

By Martina M. McGrath, MD
February 23, 2017

Cardiac troponins are highly sensitive biomarkers of myocardial injury, and acute rises are a central feature in diagnosis of acute myocardial ischemia. However, observational studies have also suggested that increased levels of high-sensitivity troponin are associated with increased cardiovascular mortality in population-based studies.1,2  This raises the question as to whether the level of high-sensitivity troponin could usefully predict a patient’s future risk of cardiovascular events. Continue reading “Does High-Sensitivity Cardiac Troponin Predict Future Cardiac Events?”